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SQI: Simpson Querry Institute

Evangelos Kiskinis

  • Assistant Professor of Neurology, Division of Neuromuscular Disease
  • Assistant Professor of Physiology

PhD (2008), Imperial College London

The Kiskinis lab seeks to harness the power of pluripotent stem cells to understand how neuronal function is impaired in neurological disease. We utilize patient-specific induced pluripotent stem cells (iPSCs) and direct reprogramming to generate distinct neuronal subtypes of the central nervous system (CNS), including motor neurons, astrocytes, cortical excitatory and inhibitory neurons. We study these cells by a combination of genomic, biochemical and functional electrophysiological assays. In alignment with the mission of SQI our overall objective is to develop models of human neurological diseases by combining iPSC and bionanotechnology approaches for the therapeutic benefit of patients.

Areas of Interest

Induced Pluripotent Stem Cells (iPSCs), Modeling Neurological Disease, Nanotechnology, Neural Organoids